For COPD a Combination of Ipratropium Bromide and Albuterol Sulfate Is More Effective Than Albuterol Base

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Levalbuterol is not more cost-effective than albuterol for COPD.

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The combination of ipratropium and albuterol is more effective than either agent alone.

Anticholinergic bronchodilators have been used since the beginning of recorded time. The datura genus of plants that contains anticholinergic alkaloids, including atropine, has been used by man for several thousand years for "recreational and various nefarious purposes."1 The anticholinergics have been used as bronchodilators for at least 300 years.2 Stramonium powders, burned and inhaled, are ...

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Effects of Inhaled Albuterol and Ipratropium Bromide

Study objective: Systemic administration of P-agonist and anticholinergic drugs markedly impair normal autonomic heart rate control. The purpose of this study was to quantify and compare the effects of therapeutic doses of inhaled albuterol and ipratropium on autonomic control of the cardiovascular system. Design: Randomized, double-blind, placebo-controlled, crossover design study. Setting: Te...

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COPD patient satisfaction with ipratropium bromide/albuterol delivered via Respimat: a randomized, controlled study

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 1999

ISSN: 0003-9926

DOI: 10.1001/archinte.159.2.156